Stibosan (Von Heyden "471")
نویسنده
چکیده
The Solution.?The required dose should be dissolved in sterile distilled water in order to make a 5 per cent, solution, i.e., 0.05 gramme will require 1 c.c., 0.1 gramme 2 c.c., 0.2 gramme 4 c.c., and 0.3 gramme 6 c.c. The solution should not be boiled and should be prepared freshly. (We have used solutions that have been kept 48 and even 72 hours without any ill-effects but as there is danger of the solution becoming contaminated, if kept, it is advisable to prepare the solution each day.)
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Urea-Stibol in the Treatment of Kala-Azar
" stibacetin," which was the first aromatic compound of antimony to be used in the treatment of leishmaniasis, many aromatic compounds of antimony have been introduced. Von Heyden also introduced sodium meta-chloro-para-acetylamino stibinate, known as No. 471 or " stibosan," and an amine salt of p-amino-phenyl-stibinic acid known as No. 693 iboth of which proved to be very effective in the trea...
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